Reduce blood sugar with sake [ALA]! Proving overseas that mitochondrial enhancement will extend lifespan

Do you know Mr. Great Yoshita?

One of the members of the Takeshi Corps, formed by Beat Takeshi's apprentices before, is a comedy talent with a friendly round smile.

He suffers from diabetes and is undergoing dialysis, but has recently been admitted to the hospital.

He now thinks, “If I started treating diabetes earlier, I should have started dialysis a few years later, but I was regretful that I had sweetened diabetes.”

He looked at the blog he gave his courage and published his illness, and if he knew about the ingredients contained in the sake called ALA, he could have prevented diabetes at an unaffected stage. I have to regret not having it.

ALA is a nutrient that invigorates the weak energy production plant “mitochondrion”. If mitochondria are weak, it can cause all kinds of diseases. Of course, diabetes is also true.

This time,

  • 1 billion Japanese
  • 2 people have diabetes
  • Relationship between ALA and mitochondria in sake
  • How to extend healthy life expectancy by supplying ALA to mitochondria

I will explain.

Diabetes that was sweet

dialysis

Mr. Great Yoshio's dialysis is 3 times a week, staying in bed for 1 hours every 5 times, so 15 time will be taken a week.

Since he is an entertainer who belongs to the office, the schedule will be flexible, such as choosing the day to receive work, but it is difficult if it is a general office worker.

You may not be able to travel because of dialysis, which may interfere with your work. More than that, it comes with a financial burden.

Monthly 300,000 yen by artificial dialysis

A man in a suit putting out a calculator in front

Despite Great Yoshita's fall at home in 1995 and the hospital told him that he had to give a lifetime insulin injection,Repeatedly stop going to the hospital when things get better, and take care of the hospital again when things get worseThere is a past.

In the meantime, I fell down while recording on TV,Chronic renal failure resulting from diabetic nephropathyIt was.

And now, Mr. Great Yoshio has paid 1 times 25,000 yen as an artificial dialysis fee. What a month 300,000 yen! This is a very painful expense.

Diabetic nephropathyIs a symptom seen in people who have diabetes for more than 10 years. The glomerulus of the kidney is damaged and gradually progresses to generalized arteriosclerosis and chronic renal failure.

With chronic renal failureIs a state in which the kidney's function of removing waste in the blood is lost. Once kidney function is lost, it almost never recovers.

Click here for "Great Yoshita's Diabetes Mellitus"

Silent killer diabetes

Silent killer diabetes

Diabetes is a disease in which the amount of sugar in the blood increases.

Natural healing is unlikely and severe diets and weight loss are awaiting.

RemissionThere are things to do,Never cure. Once you are derailed from diet and gain weight, treatment begins again.

* Remission is a condition as if the disease was cured. Regarding diabetes, it is “a state in which normal blood sugar levels can be maintained without drugs”.

Diabetes can be said to be a lifelong disease. However, there is no subjective symptom.

You have knowledge of diabetes, but don't you think you're planning to become a member of diabetes?

Diabetes isDamaged blood vessels in the body without noticing, hardening the arteryI will let you.

Later, by developing complications in the heart and kidneys, it is scary because you finally realize the seriousness of the situation.

By having diabetesNeurosis, retinopathy, nephropathy also develops, but Alzheimer's disease, cancer, myocardial infarction, stroke, cerebral infarctionRisks such as increase.

Diabetes reserve army can not be relieved even if "no abnormality" in the medical examination

A woman who says that safety is prohibited even if there is no abnormality in the diabetes test

The probability of getting diabetes is said to be 5 by Japanese adult 1, but this is actually a number that started out from a medical examination.The health check is usually performed on an empty stomach, so there is no abnormality in the diabetes test..

People with postprandial hyperglycemia are at high risk of heart disease

If you really want to know if you ’re in the diabetes reserve,"Postprandial hyperglycemia (blood sugar spike)Within 2 hours after mealsIt is recommended that you investigate.

Because people with postprandial hyperglycemiaMore likely to die from cardiovascular disease than normal diabeticsIt is.

* Postprandial hyperglycemia (blood glucose spike) is a rapid increase in blood glucose within a short time after a meal, and a rapid decrease in about 2 time. It is said that cells in blood vessels are more likely to be damaged by people who have rapid blood sugar level fluctuations than those who have high and stable blood sugar levels.

“5 people to 1 people” is wrong, “2 people to 1 people” is diabetes reserve

According to a large diabetes test in China, 11% were diabetic and 36% were pre-diabetic. Indeed2 people have diabetesIt is related to. By the way, this test was done at 2 time after meal, so it includes people with postprandial hyperglycemia.

If you do the same inspection in Japan,Similar percentages due to ethnic similarities with ChineseThere are concerns.

Even people who look healthy on the surface are more likely to be eaten by sugar inside the body.

Stop diabetes at the non-disease stage!

stop

In order to prevent 2 people from becoming 1 diabetics, shifting to a lifestyle that avoids diabetes now has significant implications for improving quality of life. Most people who don't have a life if they spend 300,000 yen every month on dialysis.

By the way, do you know the word “not sick”? In brief,

"Unhealthy, less than ill" condition. Somehow I'm dull and I'm not fine, but I'm not sick yet. However, I am certain that I will get sick in the future.

Already late after getting sick.Predicting diseases that may be affected in the future, and stopping progress in an unaffected stateIs required. In the way of dealing with non-illnessDifference in aging speedAppears,Life differenceIt also leads to.

In reality, if you find a problem with regular check-ups, you can follow the doctor's instructions to prevent the disease.

In addition, we Japanese sake fans may be able to maintain their health by drinking an appropriate amount of sake.

そのKeywords are mitochondria and ALA.

Health and disease depend on mitochondria

Mitochondria

Mitochondria are small organelles that exist in 60 trillion cells in our body (there is also the theory that there are 37 trillion cells).Something like a power plant.

We take care of the energy that mitochondria produce, not only when we move our bodies, but also when our hearts move, when we are thinking, and when the gastrointestinal digests what we eat.Mitochondria is 95% of our total energyIs making.

Functions of mitochondria

Since mitochondria also do the following tasks, it is said to be the “control tower in the cell”.

  • Metabolizes glucose (sugar)
  • Producing ATP as an energy plant
  • Leads cells with damaged DNA to apoptosis (because it can cause cancer, etc.)
  • Synthesis of steroids and heme (red organic pigment containing iron in hemoglobin)
  • Regulation of immunity and metabolic function

 

Normally mitochondria do their jobs well, but onceIf the number of mitochondria decreases or the work decreases, the cause of the body malfunction, disease, and agingIt will be.

 

"Illness and aging is a condition where the mitochondria are insufficient or not healthy"A big presence that affects the state of the human bodySuch you.

What happens when mitochondria's work declines?

A woman falling down on the sofa

When you are hot in the summer, for example, you can eat nutritious food.

However, no matter how much nutrition is taken with the mitochondria being reduced and weakenedATP (adenosine triphosphate), the raw material for energy, cannot be produced.

That's why something like "I've eaten so much, but my body gets sluggish ... why?"

Reasons for weakening mitochondria

The causes of mitochondrial weakness are aging, eating habits, lack of exercise, and stress. In today's life with stressful stress due to the high sugar content, not only does the mitochondria weaken, but the number decreases.

In fact,The body of a diabetic patient has half the amount of mitochondriaThere is only.

Decreased mitochondria causes cell weakening → pathogenesis

Mitochondria are present in cells throughout the body.

By weakening the mitochondria, the energy in the cell is reduced and the cell is damaged.The part where damaged cells are present is illIt appears in the form of

For example,

Dementia if brain neurons are damagedbecome,Arteriosclerosis if vascular cells are damagedTied to

Cosmetically, mitochondrial weakening is waiting for a painful reality for women.

Since mitochondria also have a function to reincarnate cells,Skin turnover (No skin reincarnation), no matter how expensive cosmetics are applied from the outside.

Increased spots and wrinklesSeen older than people of the same ageIt looks like

Non-disease is a condition in which mitochondrial activity is insufficient

Women who say that mitochondrial activity is weakened

As explained above for non-disease,

Non-disease is "Insufficient mitochondria or weak mitochondrial activity"Status

It can also be said.

That meansIf mitochondria work enough, you won't get sickmust.

The theory is extremely simple.

In shortIf you have mitochondria increase and get healthy, you will return from an unaffected state to healthYou can.

Mitochondrial augmentation strategy

So how do mitochondria become healthy and proliferate?

In fact, mitochondria will increase in a situation where “energy is needed”.Reliable and happy typeSuch you.

If the body doesn't need energy, mitochondria won't work, and cells that have been reduced by energy are weakened and appear in the form of disease

I explained.

That meansMaking full use of “Reliable Tech” that mitochondria are pleased withJust do it.

Reliable tech ① 30 minutes / week 3 exercises that lightly sweat

Exercise image

If exercise continues, mitochondria will determine that this person does not need much energy, and will reduce ATP production. Mitochondria are also “shibuchin”.

In order to convey to the mitochondria that you want more energy, you need a lot of exercise.

At first you will get a breath, but as you continue, you will find yourself getting used to it. That is evidence that the number of mitochondria has increased and the activity has increased.

Mitochondria is red muscleIs included in manyAerobic exercise is recommended as the type of exercise.

* Red muscle is also called “slow muscle” and can contract for a long time. Ideal for exercise while consuming oxygen.

Reliable tech ② Petite fasting 1 times / week

Food image

If you always eat until you are full, mitochondria will miss energy production.

However, if you make fasting once a week or reduce the total calories of 1 days to create a “starvation state”, mitochondria will create energy and divide and proliferate.

Replenishment tech ③ ALA intake with sake

I want to add to the endMitochondrial enhancement method actively incorporates ALA from foodこと.

ALA is a kind of amino acid “5-aminolevulinic acid” and is the only amino acid that is the raw material of hemoglobin in the blood.Substances that enhance mitochondrial function.

It is said that ALA was also involved when the first life was born on Earth.It plays an important role in life support.

ALA is also produced in mitochondriaHowever, if there is a shortage, mitochondrial activity will weaken and must be replenished.

“If it ’s important, it ’s only in special food,”High concentration in sakeIt is

ALA is a lot in fermented foods,The amount of ALA in sake isSo, the wine of 2 rank is greatly separated.

Black vinegar, which is likely to contribute to health, has been hailed as a health food, but the amount of ALA in black vinegar is only the 1 / 3 amount of sake.

Click here if you are worried that drinking alcohol will cause diabetes.

Sake and diabetes were unrelated! What is the function of Japanese sake to prevent blood sugar levels from rising sharply?

Blood glucose level is improved by ALA which rejuvenates mitochondria

However, there may be some people who have a sludi rush to ask, “What is the relationship between diabetes and ALA?” Before explaining it, let's know about the strong stress experienced by diabetics.

Diabetes and great stress

The first thing people who have been pointed out to diabetes and its reserves should do is reduce sugar intake.Dietary restrictions".

But,

What you have eaten up to now is forbidden, and you will be forced to make useless days when you can't eat sweet, seasoned foods, or eat too much. By the way, the exercise that you don't want to do is forced, and naturally the stress builds up.

Stress in modern society can generate so much active oxygen that it is said to be the source of all illnesses, and it can further exacerbate the condition.

there,It is studied whether there is a way to improve glucose metabolism abnormality from another angle, not just dietary restrictionsIt began.

ALA research results

ALA has emerged as a result of such research.

There was a difference in the blood glucose level of 12 time after meal between the group that took ALA with meals for 2 weeks and the group that did not.

In the ALA intake group, fasting and postprandial blood glucose levels declined, especially in those who were about to become diabetic, and the rate of decline was greater. .

Increased metabolism by enhancing ALA in mitochondria

ALA functions in mitochondria, which controls metabolism, and converts sugar and fat into energy.

But,

ALA decreases as people get older. It begins to decrease gradually from the age of 17 and decreases to half the amount after the age of 40.

This is why many people develop diabetes after 40.

Diabetes is not the only disease caused by a decrease in ALA.

Mitochondria with reduced amounts of ALA will lose activity. Decreased mitochondria have reduced function and generate active oxygen. Cells also weaken and cannot remove active oxygen, which promotes renal aging and malignant (cancerous) surrounding tissues.

Before that happens, it is recommended to replenish ALA.

Let's replenish not only ALA but also iron

The reason iron is needed is to make up for heme in the cell.

When heme in the cell is deficient, glycogen synthesis becomes abnormal, leading to the development of diabetes.

Glycogen synthesis abnormalities may be improved by administration of ALA, so the combination with iron seems to increase the effect.

ALA content in food

The main foods that contain ALA are listed below.

Food name ALA content (µg / 100g)
Sake 70~353
Wine 110~173
Black vinegar 150
Octopus 78.4
Skewered Shitake Mushroom 5~45
squid 38
banana 31.6
Natto 25

The amount of ALA required for 1 days is 0.5 to 2mg.

* For sake, 100ml of ALA can be taken with 0.35ml.

 

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A post shared by pub (@oiwake_teppen) – November 2017, 11 13:9 AM PST


Reference document

-ResearchGate [Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study]

-American Journal of Physiology [Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in culture]

-ScienceDaily [High prevalence of diabetes, prediabetes in China]

-Federation of American Societies for Experimental Biology [Mitochondrial dysfunction causes Ca2 + overload and ECM degradation–mediated muscle damage in C. elegans]

-ResearchGate `` 5-Aminolevulinic acid, a precursor of heme, reduces both fasting and postprandial glucose levels in mildly hyperglycemic subjects ''

-KAKEN [Elucidation of the molecular mechanism of glucose metabolism abnormality caused by heme deficiency]

 

* This article describes the author's own views based on reference information. Please use the information at your own risk and judgment. The author and publisher are not responsible for any direct or indirect damages resulting from this. Please note.